Quantitative analysis of DNA extracted from the rectal mucosa of patients with colorectal disease

Origin Sciences (UK)0 个研究点目标入组 100 人开始时间: 2010年6月16日最近更新: 2016年10月17日

适应症

试验速览

暂无简介。

•1. Male and female patients aged 18 or over
•2. Patients who have given written informed consent
•3. If a woman of child-bearing potential, must have given a negative pregnancy test

•1. Patients less than 18 years old
•2. Patients taking part in another clinical study
•3. Patients unable to give clear written informed consent to the study
•4. Patients with confirmed inflammatory bowel disease (IBD)
•5. Patients with confirmed or suspected anal cancer
•6. Patients with who have had any previous gastro-intestinal malignancy
•7. Patients who have undergone previous colonic resection
•8. Patients who have undergone chemotherapy or radiotherapy anytime within the last 6 months
•9. Patients who have received any form of bowel preparation or contrast medium within the 14 days preceding the test
•10. Patients who have received any form of anaesthesia in the 48 hours preceding the test
•11. Patients with clear evidence of rectal cancer at proctoscope examination
•12. Patients with an anal fissure, anal fistula, advanced haemorrhoids or any other condition that may make proctoscope introduction painful and/or dangerous in the eyes of the investigator
•13. Patients with a faecally loaded rectum at proctoscope examination
•14. Women who are pregnant or suspect that they may be pregnant
•15. Patients with known Hepatitis B or HIV infection
•16. Patients suffering from chronic alcohol abuse (over 30 units consumed per week on average)
•17. Patients with a history of allergic reactions to compounds of similar chemical or biological composition to the device
•18. Patients unable to comply with the protocol requirements (compliance)

发起方

Origin Sciences (UK)