Sevoflurane in Electroconvulsive Therapy

Phase 4

Completed

• Conditions: ECT; Anesthesia
• Interventions: Drug: sevorane

• Registration Number: NCT01905904
• Lead Sponsor: Inonu University

Brief Summary

The purpose of the study was to investigate the effects of different doses of sevoflurane used in electroconvulsive therapy (ECT) on duration of seizure, hemodynamic response and recovery profiles

Detailed Description

Motor (EMG) and electroencephalography seizure duration (EEG), heart rate (HR) and mean arterial pressure (MAP) values, and recovery times were recorded.

Study Timeline

• Study Start: 2013-03
• Primary Completion: 2013-05
• Study Completion: 2013-06
• Study First Submitted: 2013-07-16
• Study First Submitted QC: 2013-07-22
• Study First Posted: 2013-07-23
• Status Verified: 2019-05
• Last Update Submitted: 2019-05-15
• Last Update Posted: 2019-05-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 25

Inclusion Criteria

• Study included 25 patients of American Society of Anesthesiologists (ASA) physical status I-II aged between 18-60 years who were scheduled for ECT sessions under general anesthesia

Exclusion Criteria

• Pregnancy
• Cerebrovascular disease
• Epilepsy
• Unstable cardiovascular disease
• Chronic obstructive pulmonary disease; and
• Renal or hepatic failure

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
sevorane	sevorane	Sevorane 4% concentration during anesthesia induction
sevorane %7	sevorane	Sevorane 7% concentration during anesthesia induction

Primary Outcome Measures

Name	Time	Method
sevoflurane used in electroconvulsive therapy (ECT) on duration of seizure	taken prior to the seizure

Secondary Outcome Measures

Name	Time	Method
sevoflurane used in electroconvulsive therapy (ECT) on hemodynamic response.	taken prior to the seizure

Trial Locations

Locations (1)

Inonu Unıversity School of Medicine; 🇹🇷 Malatya, Turkey