The role of synbiotic in the prevention of necrotizing enterocolitis in preterm neonates.

Phase 1

• Conditions: ecrotizing enterocolitis.; Necrotizing enterocolitis of newborn

• Registration Number: IRCT20180519039715N2
• Lead Sponsor: Kermanshah University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 5 November 2019

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 118

Inclusion Criteria

Admission to the Neonatal Intensive Care Unit (NICU) at birth
Gestational age less than 34 weeks (early preterm)
Elapse of maximum 28 days after birth
birth weight 1000 to 1500 gr
Lack of affliction with gastrointestinal obstruction, amphalocele, gastroschis, congenital heart disease, clinical or proven sepsis, grade 2 and 3 asphyxia
No history of immunodeficiency among relatives
No maternal drug addiction
Avoidance of breast-feeding to feed neonate
Avoidance of synbiotic supplementation consumption by the infant mother

Exclusion Criteria

Gestational age over 34 weeks
Elapse of over 28 days since the birth of infant
Birth weight less than 1000 (due to high mortality rates) and more than 1500 gr
Neonate’s affliction with gastrointestinal obstruction, amphalocele, gastroschis, congenital heart diseases, clinical or proven sepsis, grade 2 and grade 3 asphyxia
History of immunodeficiency among relatives
Neonate with addicted mother
Babies fed with powdered milk
Oral administration of synbiotic supplement by neonate’s mother

Study & Design

• Study Type: interventional
• Study Design: Not specified