Study of the effect of symbiotics on preventing ventilator- associated pneumonia
Phase 3
Recruiting
- Conditions
- Condition 1: Ventilator-associated pneumonia. Condition 2: Duration of mechanical ventilation. Condition 3: Duration of ICU stay. Condition 4: Duration of hospital stay. Condition 5: Mortality rate.J20-J22Other acute lower respiratory infections
- Registration Number
- IRCT20220912055944N1
- Lead Sponsor
- Esfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 70
Inclusion Criteria
Children supported by mechanical ventilation for at least 48 hours and without primary immunodeficiency
Exclusion Criteria
Primary immunodeficiency
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Percentage of patients who were infected with ventilator-associated pneumonia. Timepoint: At the beginning, middle and the end of the study. Method of measurement: Nonbronchoscopic bronchoalveolar lavage (NB-BAL).
- Secondary Outcome Measures
Name Time Method Duration of ventilator-associated pneumonia treatment. Timepoint: Beginning and end of the treatment. Method of measurement: Number of the days that ventilator-associated pneumonia was treated.;Duration of mechanical ventilation. Timepoint: Beginning and end of the mechanical ventilation. Method of measurement: Number of the days the patients were under mechanical ventilation.;Duration of hospitalization in pediatric intensive care unit. Timepoint: Beginning and end of the hospitalization in pediatric intensive care unit. Method of measurement: Number of the days the patients were hospitalized in pediatric intensive care unit.;Duration of hospitalization. Timepoint: Beginning and end of the hospitalization. Method of measurement: Number of the days the patients were hospitalized.;Mortality rate. Timepoint: End of the study. Method of measurement: Counting the deaths.