Garlic With Lime Juice and Chlorhexidine Mouthwash

Not Applicable

• Conditions: Gingival Bleeding
• Interventions: Drug: garlic with lime mouth wash; Drug: chlorhexidine

• Registration Number: NCT03105960
• Lead Sponsor: Cairo University

Brief Summary

the study about herbal mouthwash. it is clinical trial .the investigator will compare between chlorhexidine mouthwash and garlic with lime juice mouthwash.and their effect on gingival bleeding and plaque and salivary bacteria.

Detailed Description

the study about herbal mouth wash. it is clinical trial .the investigator will compare between chlorhexidine mouthwash and garlic with lime juice mouthwash.and show their effect on gingival bleeding and strepococcus bacteria present in saliva and plaque.

1. Preparation of garlic with lime juice will occur under aseptic condition.and give it to the first group.

provide chlorhexidine to the second group.

2. Collection of plaque and saliva samples will be obtained from children who fulfilled the inclusion criteria.

3. Asses gingival condition by asking patient.

4. Subjects will be instructed to rinse for 14 days, twice daily.

5. Morning after breakfast and night before going to bed.

6. With 10 ml (undiluted) of the assigned mouthwash for 30 s and then expectorate the rinse.

7. Again after 14 days, the saliva and plaque samples will be taken and inoculated on blood agar plates to determine the colony count and the gingival index by loe and illness will be assessed.

Study Timeline

• Study Start: 2017-03-10
• Study First Submitted: 2017-03-21
• Status Verified: 2017-04
• Study First Submitted QC: 2017-04-04
• Last Update Submitted: 2017-04-04
• Study First Posted: 2017-04-10
• Last Update Posted: 2017-04-10
• Primary Completion: 2017-06-01
• Study Completion: 2017-06-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 36

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
garlic with lime juice mouthwash	garlic with lime mouth wash	garlic with lime juice mouthwash is herbal antimicrobial .children were instructed to rinse for 14 days, twice daily, ,10 ml (undiluted) for 30 second and then expectorate . To prepare garlic with lime mouth rinse, 100 g of fresh, washed garlic cloves was macerated in a sterile, ceramic mortar and water was added to obtain a homogenate which was then filtered off with a sterile muslin cloth. the final concentration of the solution was determined to be 1 g/100 ml. About 100 ml of lime juice was extracted from fresh lemons using a juice extractor and added to the garlic extract.
chlorhexidine mouthwash	chlorhexidine	chlorhexidine is antimicrobial, antiplaque mouthwash 10 ml (undiluted) for 30 second twice daily and then expectorate for 14 days. it is commercial mouthwash .

Primary Outcome Measures

Name	Time	Method
gingival bleading	15 day	bleeding of gingiva asses by yes or no

Secondary Outcome Measures

Name	Time	Method
Streptococcal count in saliva and plaque	15 day	Streptococcal count in saliva and plaque

Trial Locations

Locations (1)

Manal Sayed Abdel Latief; 🇪🇬 Helwan, Cairo, Egypt