Higher vs. Lower Doses of Steroids in Patients with COVID-19
- Conditions
- Health Condition 1: B972- Coronavirus as the cause of diseases classified elsewhere
- Registration Number
- CTRI/2020/10/028731
- Lead Sponsor
- Professor Anders Perner
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 0
All the following criteria must be fulfilled:
Aged 18 years or above AND
Confirmed SARS-CoV-2(COVID-19) requiring hospitalisation AND
Use of one of the following:
Invasive mechanical ventilation OR
•Non-invasive ventilation or continuous use of continuous positive airway pressure (CPAP) for hypoxia OR
Oxygen supplementation with an oxygen flow of at least 10 L/min independent of delivery system
Use of systemic corticosteroids for other indications than COVID-19 in doses higher than 6 mg dexamethasone equivalents
Use of systemic corticosteroids for COVID-19 for 5 consecutive days or more
Invasive fungal infection
ctive tuberculosis
Fertile woman ( <60 years of age) with positive urine human gonadotropin (hCG) or plasma-hCG
Known hypersensitivity to dexamethasone
Previously randomised into the COVID STEROID 2 trial
Informed consent not obtainable
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method