跳至主要内容
临床试验/CTRI/2025/07/091019
CTRI/2025/07/091019尚未招募1 期

Efficacy of low intensity resistance exercise training on strength and endurance in patients with organophosphate induced delayed polyneuropathy

VENKATESAN K1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2025年8月12日最近更新:

试验速览

阶段
1 期
状态
尚未招募
发起方
入组人数
60
试验地点
1
主要终点
Level of Endurance on 6 Minute walk test, strength on MRC grading and level of muscle activity with CPK

研究概览

简要总结

**TITLE:**Efficacy of Low Intensity Resistance Exercises on strength and endurance in patients with Organophosphate induced Delayed Polyneuropathy

**Abstract:**Approximately 3 million people globally are exposed to organophosphates, resulting in around 3,00,000 fatalities. In the clinical settings the clinicians found that, many of the OPC poisoning patients get readmission after discharging from the ICUs due to OPIDPN. And also, the review follow-up by the clinical advisors evident around 40percent of patients gets readmitted and 30% mortalities at home after being bedridden state.**Aim Of the Study:**To determine the effect of low intensity resisted exercise on strength and endurance of the patients with OPIDPN. **Methodology:**This Quasi-Experimental Study will include the OPIDPN patients between the age group of 25-44 years based on the defined Inclusion & exclusion criteria. The patients will undergo OPIDPN rehabilitation exercise program for 4 weeks in Vivekanandha Medical Care Hospital, Namakkal. The patients will undergo pre-test and post – test evaluation. The collected data will be taken for Statistical analysis using Paired ‘t’ test. This study expects the effect of Low Intensity Resistance Exercises on strength and endurance in patients with Organophosphate induced Delayed Polyneuropathy.

研究设计

研究类型
Interventional
分配方式
Na
盲法
None

入排标准

年龄范围
25.00 Year(s) 至 44.00 Year(s)(—)
性别
All

入选标准

  • Patients who undergone Intensive Care Unit admission following OPC poisoning Patients developed OPIDPN within 3 months.
  • Patients with lower limb muscle power MRC GREATER THAN 3 Patients with adequate standing balance Patients with adequate interpersonal communication Patients concerning the exercise program.

排除标准

  • Patients who had recurrent incidence of OPC poisoning and other poisoning Patients with chronic co-morbidities like HTN, DM, hormonal diseases, bronchial asthma Patients who were on mechanical ventilator more than 5 days Patient with previous history of neuromuscular diseases Patients with locomotor disabilities Patients who have precious history of Cardiac Disease Patients with diabetic polyneuropathy, Hepatitis B infection, autoimmune disorders, HIV, kidney disease, liver diseases.

结局指标

主要结局

Level of Endurance on 6 Minute walk test, strength on MRC grading and level of muscle activity with CPK

时间窗: At baseline (beginning) and end of the 4th week.

次要结局

未报告次要终点

研究者

发起方
VENKATESAN K
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

VENKATESAN K

Ph.D Scholar

研究点 (1)

Loading locations...

相似试验