Effect of HCG on Endometrial Preparation in Frozen Embryo Transfer

Active, not recruiting

• Conditions: IVF
• Interventions: Drug: hCG + estradiol; Other: Observation arm

• Registration Number: NCT06577181
• Lead Sponsor: Assiut University

Brief Summary

Intramuscular injection of HCG to prepare endometrium for frozen embryo transfer

Detailed Description

This study is to compare the effectiveness of intramuscular injections of Human chorionic gonadotropins in preparing the endometrium for frozen embryo transfer compared to the control group who did not receive the injection

Study Timeline

• Study Start: 2024-05-10
• Status Verified: 2024-08
• Study First Submitted: 2024-08-27
• Study First Submitted QC: 2024-08-27
• Last Update Submitted: 2024-08-27
• Study First Posted: 2024-08-29
• Last Update Posted: 2024-08-29
• Primary Completion: 2025-05-10
• Study Completion: 2026-05-10

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: Female
• Target Recruitment: 50

Inclusion Criteria

1. Infertile women being prepared for frozen embryo transfer (FET) in an ART program

Exclusion Criteria

• (1) Use of preimplantation genetic test.

2. History of recurrent spontaneous abortion.
3. Presence of congenital uterine malformations.
4. Use of sequential embryo transfer.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Women undergoing preparation for Embryo transfer	hCG + estradiol	Group who received intramuscular injection of HCG before embryo transfer
Women undergoing preparation for Embryo transfer 1	Observation arm	Group who did not receive intramuscular injection of HCG before embryo transfer

Primary Outcome Measures

Name	Time	Method
Clinical pregnancy	2months	Presence of at least one gestational sac inside the uterus 28 days after embryo transfer

Trial Locations

Locations (1)

Assiut university; 🇪🇬 Assiut, Egypt