Virtual visual cues to reduce freezing in Parkinson’s disease: an explorative study

Conditions: Parkinson's Disease
Freezing of Gait
ziekte van Parkinson
Bevriezen van lopen

Registration Number: NL-OMON21397

Lead Sponsor: niversity of Twente

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: Not specified

Target Recruitment: 35

Inclusion Criteria

In order to be eligible to participate in this study, a subject must meet all of the following criteria:

•age > 18 years

Exclusion Criteria

A potential subject who meets any of the following criteria will be excluded from participation in this study:

•Significant cognitive impairments. This is defined as a score on the mini mental state examination (MMSE (30)) equal to or smaller than 14, or a score on the frontal assessment battery (FAB(31)) of equal to or smaller than 13.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The main study parameters are ‘freezing severity’, ‘step time variability variability’, ‘modal footstep latency’, ‘motor initiation’ and ‘stopping performance ‘. The study parameters are contrasted between: 1) Cue responsiveness (during VR foot pedalling and overground walking), and 2) the correlation between freezing during overground walking and VR foot pedalling; both uncued and visually cued.

Secondary Outcome Measures

Name	Time	Method
Secondary endpoints are: association of freezing during VR pedalling with subjective FOG severity, and user experience with the paradigm.<br /><br>Other study parameters measured are: age, Hoehn-Yahr-stage, UPDRS part III score, and scores on the mini mental state examination (MMSE) and frontal assessment battery (FAB).