Augmented Reality cues to reduce Freezing of Gait during turning in persons with Parkinson*s disease

Completed

Conditions: Freezing of gait in Parkinson's Disease
10028037

Registration Number: NL-OMON46306

Lead Sponsor: niversiteit Twente

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 16

Inclusion Criteria

In order to be eligible to participate in this study, a subject must meet all of the following criteria:
* Age > 18 years
* Diagnosed with idiopathic Parkinson*s disease according to the UK Brain Bank Criteria [29]
* Written informed consent
* Presence of FOG (defined as a score of 1 on question 1 from the NFOGQ[30]: *have you ever experienced FOG in the past month?*)
* Disabling/regular FOG (defined as a score of 3 *Very often, more than one time a day* on question 2 from the NFOGQ: *How often do you experience FOG?*)
* Normal or corrected to normal vision.

Exclusion Criteria

A potential subject who meets any of the following criteria will be excluded from participation in this study:
* Comorbidities that cause severe gait impairment (e.g. severe arthrosis or neuropathy)
* Comorbidities that cause severe vision impairment (e.g. severe maculopathy)
* Severe cognitive impairments (MMSE <24) or or a score on the frontal assessment battery (FAB) of equal to or smaller than 13.
* Inability to perform a 180 degree turn around the axis unaided (e.g.: without the help of a walking aid or the direct help of a person).
* Severe uncorrected bilateral hearing impairment, preventing the participant to hear the metronome.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main endpoint is FOG severity, as defined by the parameters: fraction of<br /><br>time spent with freezing; number of freezing episodes; duration of freezing.<br /><br>The occurrence of FOG is determined by evaluation of the video recordings by<br /><br>two independent trained raters. The FOG severity will be compared amongst the<br /><br>different cueing conditions.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>A secondary endpoint is quantification of the turns with parameters of<br /><br>interest: lateral weight shifting; turn duration; cadence; step time; step<br /><br>height; footstep latency; motor initiation and stopping performance. Another<br /><br>secondary endpoint is the association of FOG severity parameters obtained from<br /><br>the video recordings, with FOG detection parameters calculated using data from<br /><br>the accelerometers.</p><br>