ISRCTN58995463已完成未知
Do ACE inhibitors reduce postural instability in older people? Towards a novel approach to falls prevention
niversity of Dundee/NHS Tayside (UK)0 个研究点目标入组 80 人开始时间: 2013年8月2日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 80
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Aged 65 years or over
- •2. One or more self-reported falls in previous 12 months
- •3. Been assessed at a Medicine for the Elderly Falls clinic in previous 2 years
- •4. Able to provide informed consent
排除标准
- •1. Already taking ACE inhibitor (ACEi) or Angiotensin Renal Blocker (ARB)
- •2. Contraindication to ACE inhibitor use [previous intolerance; significant aortic outflow obstruction (peak gradient >30mmHg) serum potassium >5.0mmol/l; eGFR<30ml/hr; serum creatinine >170umol/l]
- •3. Patients who have stopped ACEi or ARB after specialist falls assessment in the last 6 months
- •4. Clinical diagnosis of heart failure or asymptomatic left ventricular systolic dysfunction
- •5. Systolic BP>160mmHg or <100mmHg at screening visit
- •6. Wheelchair bound
- •7. Clinical diagnosis of Parkinson?s disease
- •8. Current use of Nonsteroidal anti-inflammatory drugs (NSAIDs)
- •9. Patients who have participated in any other clinical drug trial within the previous 30 days will be excluded
- •10. Intolerance to lactose
- •11. Cognitive impairment precluding informed consent
研究者
相似试验
进行中（未招募）
1 期
Preventing Falls with ACE inhibitor tabletsFalls in older peopleEUCTR2013-001677-24-GBniversity of Dundee80
已完成
2 期
Effect of ACE-inhibitors on Aortic Stiffness in Elderly Patients With Chronic Kidney DiseaseChronic Kidney DiseaseCardiovascular DiseaseNCT00874432University of Wisconsin, Madison43
进行中（未招募）
不适用
Effect of an ACE inhibitor on the exercise capacity of COPD patients. A randomized double-blind placebo-controlled study - Effect of an ACE inhibitor on the exercise capacity of COPD patientsPATIENTS AFFECTED BY COPDMedDRA version: 9.1Level: SOCClassification code 10038738EUCTR2009-009074-27-ITPROF. ALFREDO CHETTA
进行中（未招募）
1 期
ACE inhibition and mechanisms of skeletal muscle weakness in COPDChronic obstructive pulmonary disease patients who have skeletal muscle weakness.MedDRA version: 9.1Level: LLTClassification code 10010952Term: COPDEUCTR2008-004431-38-GBImperial College80
进行中（未招募）
1 期
ACE-EPIC: ACE inhibitors to enhance the effect of pulmonary rehabilitation in COPDCOPDMedDRA version: 14.1 Level: LLT Classification code 10010952 Term: COPD System Organ Class: 10038738 - Respiratory, thoracic and mediastinal disordersEUCTR2012-000413-36-GBImperial College80