EUCTR2013-001677-24-GB进行中（未招募）1 期
Do ACE inhibitors reduce postural instability in older people?: Towards a novel approach to falls prevention. - The PREFACE Study: Preventing Falls with ACE inhibitors
niversity of Dundee0 个研究点目标入组 80 人开始时间: 2013年5月24日最近更新:
适应症
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 80
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •Aged 65 years or over
- •One or more self-reported falls in previous 12 months
- •Able to provide informed consent
- •Are the trial subjects under 18? no
- •Number of subjects for this age range: 0
- •F.1.2 Adults (18-64 years) no
- •F.1.2.1 Number of subjects for this age range 0
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range 80
排除标准
- •Already taking ACE inhibitor or Angiotensin Renal Blocker (ARB);
- •Contraindication to ACE inhibitor use (previous intolerance; significant aortic outflow obstruction [peak gradient >30mmHg]; serum potassium >5.0mmol/l; eGFR<30ml/hr; serum creatinine >170umol/l)
- •Patients who have stopped ACEi or ARB after specialist falls assessment in the last 6 months;
- •Clinical diagnosis of heart failure or asymptomatic left ventricular systolic dysfunction
- •systolic BP>160mmHg or <100mmHg at screening visit;.
- •wheelchair bound
- •clinical diagnosis of Parkinson’s
- •Current use of NSAIDs
- •Patients who have participated in any other clinical drug trial within the previous 30 days will be excluded
- •Intolerance to lactose
- •cognitive impairment precluding informed consent
研究者
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