NCT03401814已完成不适用
Imaging Response to Immunotherapy and Radiation Therapy in Patients With Liver Metastases
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- Mayo Clinic
- 入组人数
- 1
- 试验地点
- 1
- 主要终点
- Quantify tissue mechanical properties of the liver and liver tumor using MRE in patients receiving radiation therapy + immunotherapy at baseline, mid-treatment and time of followup imaging determined by standard of care to assess response to therapy
研究概览
简要总结
Patients will be imaged with MRE at the time of the RT planning MRI, prior to the induction of RT and immunotherapy. Research imaging will be in addition to standard imaging studies performed at time points consistent with the standard of care (at the time of the RT planning MRI and the first clinical follow-up). An additional MRE exam will be performed at the end of treatment outside the standard of care imaging.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age ≥ 18 years
- •Diagnosis of solid cancers with the presence of one or more liver metastases
- •Minimum metastasis diameter ≥ 2 cm
- •Planning to receive radiation therapy with immunotherapy
- •Willingness to participate in mandatory imaging studies at Mayo Clinic Rochester
排除标准
- •Contraindications for MRI including claustrophobia, pace maker, metal implants, aneurism clips
- •Patients who are not able to consent
结局指标
主要结局
Quantify tissue mechanical properties of the liver and liver tumor using MRE in patients receiving radiation therapy + immunotherapy at baseline, mid-treatment and time of followup imaging determined by standard of care to assess response to therapy
时间窗: 1 year
次要结局
未报告次要终点
研究者
Sean S. Park
Radiation Oncology Consultant
Mayo Clinic
研究点 (1)
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