Parameter-based evaluation of attentional impairments in schizophrenia and their modulation by prefrontal transcranial direct current stimulation: a randomized, double-blind, sham-controlled study
Not Applicable
- Conditions
- F20F25SchizophreniaSchizoaffective disorders
- Registration Number
- DRKS00011665
- Lead Sponsor
- Klinik für Psychiatrie und Psychotherapie, Klinikum der Universität München
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
Age: 20-50 years; IQ > 85; Diagnosis: ICD-10 F20.0; F25.0; normal or corrected to normal vision (no red-green color blindness)
Exclusion Criteria
Epileptic seizures, pregnancy, metallic foreign body implants; pace maker; pregnancy; acute suicidal intent;
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Directly after and 24h after stimulation; completion of rating instrument: parametric attentional assessment based on Bundesen’s Theory of Visual Attention (TVA; Bundesen, 1990). (The assessed attentional parameters are: processing speed, visual short-term memory capacity, top-down control)
- Secondary Outcome Measures
Name Time Method Directly after stimulation: completion of Comfort Rating Scale (CRQ) to prove that the application had been running smoothly.
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie prefrontal tDCS effects on attentional impairments in schizophrenia?
How does prefrontal tDCS compare to antipsychotic medications in improving attention in F20/F25 disorders?
Which biomarkers (e.g., EEG, fMRI, COMT polymorphism) predict response to tDCS in schizophrenia patients?
What are the adverse event profiles and management strategies for prefrontal tDCS in F20/F25 populations?
Are there synergistic effects of combining tDCS with cognitive training or pharmacological agents for schizoaffective disorders?