Effect of 3 Years of Exercise on Development of Atrial Fibrillation - A "Generation 100" Substudy
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 1,567
- 试验地点
- 1
- 主要终点
- Number of persons who develop atrial fibrillation during the 3 year intervention period
研究概览
简要总结
This is a substudy of "Generation 100". In that study, 4000 healthy persons between 70 and 75 will be randomised to a moderate intensity training group, a high intensity training group or control group, with 3 years of exercise. The investigators will follow these persons and register all who develop atrial fibrillation during these 3 years, and at follow-up after ended intervention to see if there is differences in the number of persons who develop atrial fibrillation in the 3 groups.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 70 Years 至 75 Years（Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Participating in the "Generation 100" study
排除标准
- 未提供
研究组 & 干预措施
Control group
Exercise on their own. Follow current guidelines.
干预措施: Control (Behavioral)
High intensity exercise
High intensity exercise(Borg 16) in intervals.
干预措施: High intensity exercise (Behavioral)
Moderate intensity exercise
Moderate intensity exercise 3 times a week.
干预措施: Moderate intensity exercise (Behavioral)
结局指标
主要结局
Number of persons who develop atrial fibrillation during the 3 year intervention period
时间窗: 3 years
People who already have the diagnosis before randomisation will not be counted.
次要结局
- Number of persons who develop atrial fibrillation during the 6 years after randomisation(6 years)