ISRCTN98385033已完成不适用
Validation of the citric acid cough challenge using the KoKo DigiDoser system in healthy volunteers: a 4-week randomised single centre crossover study
Hull and East Yorkshire Hospitals NHS Trust (UK)0 个研究点目标入组 30 人开始时间: 2009年9月18日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 30
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Healthy male/female volunteers
- •2. Male and female subjects of at least 18 years of age
- •3. Non-smokers or, ex-smokers of at least 12 months
- •4. Forced expiratory volume in one second (FEV1) greater than 80% of predicted
排除标准
- •1. Female subjects who are pregnant, or lactating, or who are of child bearing potential but are not using contraceptive measures
- •2. Suffering from any active seasonal allergies
- •3. Suffering from concomitant disease which may interfere with study procedures or evaluation.
- •4. Subjects suffering from gastroesophageal reflux taking proton pump inhibitors or any other regular antacid therapy
- •5. Subjects suffering from post nasal drip syndrome
- •6. A recent respiratory tract infection within 6 weeks prior to entry on to study
- •7. Use of medications known to alter the cough reflex
- •8. Smoking history of greater than 10 pack years
研究者
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