PRT MEDIC: Progressive Resistance Training for MEtabolic Syndrome and Depression Integrated Care

Not Applicable

Recruiting

• Conditions: Major Depressive Disorder; Metabolic Syndrome; Type 2 Diabetes; Mental Health - Depression; Metabolic and Endocrine - Metabolic disorders; Metabolic and Endocrine - Diabetes

• Registration Number: ACTRN12617000400369
• Lead Sponsor: Dr Yorgi Mavros

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-03-17
• Last Update Posted: 15 July 2019

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 44

Inclusion Criteria

1. Major Depressive Disorder according to DSM 5 criteria,
*If not receiving any treatment; PHQ-9 of 10 or higher (moderate depression)
*If receiving treatment, PHQ-9 of 5 or higher (mild depression)
2. Metabolic syndrome according to IDF criteria
*Central obesity (Waist circumference Men; greater than or equal to 94 cm men. Women; greater than or equal to 80 cm) and any 2 of the following:
*Raised triglycerides (150 mg/dL (1.7 mmol/L) or higher, or specific treatment for this lipid abnormality)
*Low HDL cholesterol (Less than 40 mg/dL (1.03 mmol/L) in men and less than 50 mg/dL (1.29 mmol/L) in women or specific treatment for this lipid abnormality
*Hypertension (systolic BP of 130 or higher, or diastolic BP of 85 mm Hg or higher, or treatment of previously diagnosed hypertension)
*High fasting plasma glucose ((FPG) of 100 mg/dL (5.6 mmol/L) or higher.

3. at least 40 years of age
4. Not on oral hypoglycaemics or insulin therapy
5. No diagnosis of type 2 diabetes, or not found to have type 2 diabetes during the screening process
6. Sedentary - less than 150 minutes per week of structured moderate or vigorous physical activity.
7. No terminal or rapidly progressing illness, or condition that precludes participation in progressive resistance training

Exclusion Criteria

Type 2 diabetes or use of oral hypoglycaemic medication or insulin
Suicide ideation
Illegal drug use
Alcohol dependence/abuse (3 or 4 on CAGE questionnaire)
Substance abuse disorder

Study & Design

• Study Type: Interventional
• Study Design: Not specified