Osaka study of Nicorandil effect on Chronic Kidney Disease
Not Applicable
- Conditions
- Chronic kidney disease Ischemic coronary disease
- Registration Number
- JPRN-UMIN000001508
- Lead Sponsor
- Osaka University School of Medicine Department of Nephrology
- Brief Summary
Association with BNP reduction was observed.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 19
Inclusion Criteria
Not provided
Exclusion Criteria
(1)Liver cirrhosis (2)Previous organ transplantation (3)Administered anti-cancer drugs within 2 years (4)Non Japanese (5)Known HIV/AIDS
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Endothelial function measured by reactive hyperemia by pulse amplitude tonometry (RH-PAT) and augmentation index and cardiac stress marker.
- Secondary Outcome Measures
Name Time Method The primary end point is death from all causes, morbidity and mortality from cardiovascular causes, a composite of myocardial infarction, stroke, first hospitalization for heart failure or unstable angina, coronary or peripheral revascularization, or death from cardiovascular causes. The time to the first event of the composite end point of a doubling of the serum creatinine concentration, end-stage renal disease, or death is also set as a primary end point.