nravelling the role of trained immunity in cardiac allograft vasculopathy

• Conditions: Cardiac allograft vasculopathy; narrowing of the coronary arteries.; 10019280

• Registration Number: NL-OMON56885
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 22 July 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 200

Inclusion Criteria

Patient groups:
- Children and adults undergoing HTx (Primary objective 1) or
- Pediatric and adult HTx patients 5-10 years post-HTx or * 10 years post-HTx
(Primary objective 2 and secondary objectives).
- Written informed consent.

Control group:
- Healthy adolescents enrolled in the Whistler birth cohort study.
- Written informed consent, including transfer of data and blood samples to the
Trained immunity in heart transplantation study team at the Erasmus MC.

Exclusion Criteria

Acute infection (fever >38.5*C and/or clinical infectious symptoms).

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified