comparing the efficacy of methotrexate and laparoscopic salpingostomy in treating patients with ectopic pregnancy and their role in fallopian tubes patency
Phase 2
- Conditions
- ectopic pregnancy.Ectopic pregnancy
- Registration Number
- IRCT201212121556N49
- Lead Sponsor
- Vice Chancellor for Research, Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 40
Inclusion Criteria
inclusion criteria:
1- hemodynamic stability
2- ectopic mass size below 4 cm
3- patients' commitment for complete treatment and follow up
4- absence of MTX treatment contraindication
Exclusion criteria:
1- breast feeding
2- immune deficiency
3- abnormalities in hematologic system including anemia, locopenia, thrombocytopenia
4- known hypersensivity reaction to MTX
5- acute respiratory disease
6- acute peptic ulcer
7- alcoholism
8- clinical malfunction of liver and kidney
9- evidence of acute intraabdominal bleeding
10- evidence of cardiac function in the embryo
11- clinical sign and symptom of ectopic pregnancy, or B-hCG level below 5000 IU/L (with mild sign and symptoms)
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method B-hCG level. Timepoint: at the end of study. Method of measurement: blood sampling.
- Secondary Outcome Measures
Name Time Method Fallopian tubes patency. Timepoint: eight weeks after the time that B-hCG test became negative. Method of measurement: histerosalpingography.