eurocognitive and neuroimaging factors explaining differences in drug use in at-risk cannabis users.
- Conditions
- middelen afhankelijkheid (cannabis)cannabis addiction/ cannabis dependance10037176
- Registration Number
- NL-OMON32254
- Lead Sponsor
- Academisch Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 70
Male or Female, age 18-25 years, right handed;At-risk cannabis user group: 10-30 marijuana use episodes in the previous month and at least 240 marijuana use episodes in the past 2 years.;Control group 1: matched on gender and ethnicity to the cannabis user group with 1- 50 lifetime marijuana use episodes (Pope et al. 2001).;Control group 2: matched on gender and ethnicity to the cannabis user group with 0 lifetime marijuana use episodes (Pope et al. 2001).
Cannabis user group: seeking treatment or a history of treatment.
Control group 1: cannabis use during the past year. (This will be verified by urinalysis.)
Control group 2: cannabis use or ever used.
The following exclusion criteria will be in effect for all groups:
Score of more than 10 on the AUDIT screening questionnaire for alcohol related problems (Saunders et al. 1993).
Smoking more than one pack of tobacco cigarettes per day.
Current use of prescription or illicit psychoactive drugs other than marijuana.
More than 100 lifetime uses of any non-cannabinoid class of drug of abuse (Kouri et al. 1999; Pope et al. 2001).
Trying to stop alcohol or tobacco use.
Unstable medical illness (e.g., hypertension, diabetes, myocardial infarction).
Current Axis I psychiatric disorder.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Personality characteristics, behavioural scores, brainactivity, and brain<br /><br>connectivity.</p><br>
- Secondary Outcome Measures
Name Time Method <p>not applicable</p><br>