Comparison of Pre-hospital and In-hospital Iv-tPA Stroke Treatment
Completed
- Conditions
- Ischemic Stroke
- Interventions
- Other: thrombolysis in a pre-hospital setting (STEMO concept)
- Registration Number
- NCT02358772
- Lead Sponsor
- Charite University, Berlin, Germany
- Brief Summary
This is a comparison of clinical outcomes between a pre-hospital and an in-hospital thrombolysis patient registry.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 658
Inclusion Criteria
- Acute ischemic stroke diagnosis with thrombolytic treatment
- Admission via EMS
- Known premorbid status of need of assistance
- NIHSS before treatment available
- Time of onset (or last well seen) between 4:00am and 10:30pm
Exclusion Criteria
- Unknown time of onset
- In-hospital thrombolysis despite decision against treatment because of contraindications in STEMO
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Pre-hospital thrombolysis thrombolysis in a pre-hospital setting (STEMO concept) Patients with acute ischemic stroke who are cared in a specialized STroke Emergency MObile (STEMO) before admission to the Hospital and receive thrombolytic therapy (either in STEMO or in Hospital).
- Primary Outcome Measures
Name Time Method modified Rankin Scale (mRS) score three months after event dichotomized mRS 0-1 and 2-6 in patients who lived at home without assistance prior to the index stroke.
- Secondary Outcome Measures
Name Time Method modified Rankin Scale (mRS) score three months after event ordinal analysis across whole mRS range
Trial Locations
- Locations (1)
Charité
🇩🇪Berlin, Germany