Duration of Luteal Support with progesterone pessaries to improve the success rates in assisted conception: a randomised controlled trial

iverpool Women's NHS Foundation Trust (UK)0 个研究点目标入组 460 人开始时间: 2012年3月26日最近更新: 2022年5月30日

适应症

试验速览

•All patients undergoing IVF will be considered for the DOLS Trial
•1. Biochemical pregnancy confirmed by urinary pregnancy test. If positive then they will be eligible to enter the trial
•2. Progesterone treatment (2 weeks) completed up to the day of the pregnancy test
•3. Patients treated at Hewitt centre only
•4. Only those patients who have been treated with the long stimulation protocol
•5. Only patients having used Menopur for controlled ovarian stimulation

•1. All women who are undergoing frozen embryo transfer
•2. Any women not willing to take part will be excluded
•3. All diabetic, epileptic and hypertensive patients on treatment
•4. Poorly controlled asthmatics having had more than one hospital admission in the last year
•5. Patients with renal and cardiac dysfunction (Under the care of nephrologist and cardiologist respectively)
•6. Breast Cancer patients
•7. Severe liver impairment/jaundice
•8. Previous history of thromboembolism
•9. Transport centre patients, ie egg collection at Chester or Leighton
•10. Patients previously recruited to the DOLS Trial
•11. Patients who have not had a long cycle of IVF

发起方

iverpool Women's NHS Foundation Trust (UK)