The comparison of recovery profiles from the effects of two inhaled anaesthetic agents, Desflurane and Sevoflurane,in patients undergoing Laparoscopic Cholecystectomy
Not Applicable
Completed
- Conditions
- Health Condition 1: K802- Calculus of gallbladder without cholecystitisHealth Condition 2: null- Patients undergoing Laparoscopic Cholecystectomy
- Registration Number
- CTRI/2017/12/010853
- Lead Sponsor
- ot Applicable
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
1) ASA I and II patients.
2) Age group 20â??60 years.
3) Patients undergoing Laparoscopic Cholecystectomy
Exclusion Criteria
1) Moderate to severe underlying Cardiopulmonary dysfunction.
2) Moderate to severe underlying Hepatic dysfunction.
3) Moderate to severe underlying Renal dysfunction.
4) Moderate to severe underlying Endocrine dysfunction.
5) Moderate to severe underlying Neurological dysfunction.
6) Pregnancy.
7) Psychiatric disorder.
8) History of drug allergy or abuse.
9) Documented allergic reaction to the anaesthetic agent being used.
10) Patients taking CNS depressants.
11) Patient refusal to participate in the study.
12) Intra operative conversion of procedure from laparoscopic to open.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1) To compare the time taken for awakening the patient after inhalational agent is switched off. <br/ ><br>2) To compare the time taken for verbal response to occur after the inhalational agent is switched off. <br/ ><br>3) To compare the time taken for complete recovery of patient as measured by a modified Aldrete score of â?¥ 9Timepoint: 1) At the time of administering Reversal <br/ ><br>2) At the time of Extubation <br/ ><br>3) 1 minute after extubation <br/ ><br>4) 3 minutes after extubation <br/ ><br>5) 5 minutes after extubation <br/ ><br>6) 10 minutes after extubation <br/ ><br>7) 15 minutes after extubation <br/ ><br>8) 30 minutes after extubation <br/ ><br>9) Time of switching off inhalational agent( to co incide with skin closure by the surgeon) <br/ ><br>10) Time of first eye opening after switching off the agent <br/ ><br>11) Time of first verbal response after switching off the agent
- Secondary Outcome Measures
Name Time Method To document adverse effects, if any, during extubation or early recovery such as excessive secretions, coughing or laryngospasm.Timepoint: From switching off the inhalational agent, to complete awakening