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Dermatological application of a lipophilic extract of Viscum album- a multinational, retrospective case series study

Conditions
L57.0
C44.9
Actinic keratosis
Malignant neoplasm of skin, unspecified
Registration Number
DRKS00023229
Lead Sponsor
ehrstuhl für Medizintheorie, Integrative und Anthroposophische MedizinUniversität Witten/Herdecke
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
54
Inclusion Criteria

1) Actinic keratosis, cutaneous squamous cell carcinoma and basalioma
2) treatment of one of the three diagnoses between Apr 1st 2007 and July 1st 2020
3) age =18 years
4) legal capacity
5) voluntarily and written informed consent before the start of documentation
6) treatment with mistletoe resin cream in the relevant period of time

Exclusion Criteria

1) Indications other than those mentioned above that have led to therapy with mistletoe resin cream
2) Use of another topical treatment or participation in another clinical trial during the treatment period with mistletoe resin cream or four weeks before
3) Clinically relevant concomitant conditions that excessively restrict the assessment of the effect and the tolerability of the mistletoe resin cream

Study & Design

Study Type
observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Therapeutic effect:<br>- clinical response according to RECIST at the last documented date<br>Safety and tolerability :<br>- incidence, frequency and severity of adverse drug reactions according to CTCAE V5 over the whole documented course of therapy<br>
Secondary Outcome Measures
NameTimeMethod
- Clinical response rate according to RECIST (complete or partial remission) at the last documented time<br>- time from the start of therapy to best clinical response<br>- cosmetic result from the treating physician`s point of view<br>- patient satisfaction from the treating physician`s point of view<br>- descriptive representation of typical/ unfavourable/ favourable courses<br>
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