Pain relieving strategies in Fibromyalgia Patients
Not Applicable
- Conditions
- Health Condition 1: null- Fibromyalgia patients with chronic pain
- Registration Number
- CTRI/2013/12/004228
- Lead Sponsor
- AIIMS New Delhi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 90
Inclusion Criteria
Adult females (age 18-50 years) diagnosed with Fibromyalgia
Exclusion Criteria
a) Pregnant and lactating mothers.
b) Concomitant diseases such as osteomalacia, metabolic bone diseases, hyperthyroidism, and other chronic diseases.
c) When medicines such as analgesics, anti-inflammatory or psychotropic cannot be stopped for even two days.
d) A history of seizures, brain trauma, brain surgery or intracranial hypertension, pace maker or other metallic implants
e) Contra-indications for TMS
f) Inflammation in the joints
h) abnormal levels of luteinizing hormone
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The decrease in LH level in response to sucrose challenge test is deranged in fibromyalgia patients <br/ ><br> <br/ ><br>The nociceptive flexion reflex/R-III and other objective methods of pain are affected by rTMSTimepoint: Outcome name:Oral sucrose challenge test, 25gm/100 ml, pre and post rTMS, Time points:5 weeks <br/ ><br> <br/ ><br>Outcome name: Determination of Pain threshold and latency, pre and post rTMS,Time points: 5 weeks <br/ ><br> <br/ ><br> <br/ ><br>
- Secondary Outcome Measures
Name Time Method Pain in fibromyalgia is mediated by opioids <br/ ><br> <br/ ><br> <br/ ><br> <br/ ><br> <br/ ><br> <br/ ><br>rTMS is effective therapy for treatment of fibromyalgiaTimepoint: Outcome name:Oral sucrose challenge test, 25gm/100 ml, pre and post rTMS, Time points:6 months, 1 year <br/ ><br> <br/ ><br>Outcome name: rTMS, 30 min/day/20 sessions, Time points:4 weeks