Reduced urine albumin excretion in community based collaborative care in elderly Chinese with type 2 diabetes
Completed
- Conditions
- Sustained type 2 diabetes management for the elderlyNutritional, Metabolic, EndocrineNon-insulin-dependent diabetes mellitus
- Registration Number
- ISRCTN19750520
- Lead Sponsor
- Ministry of Health of the People?s Republic of China (China)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 260
Inclusion Criteria
1. Ages 60 and 80 years of age
2. Most recent HbA1c in the prior 6 months was more than or equal to 7.0%
3. Inhabitants in the respective community for more than or equal to 2 years
4. Participants with pubilic medical insurance
5. The proportion ratio is comparable in gender
Exclusion Criteria
1. Patients with cancer
2. Patients with severe cirrhosis
3. Patients with malignant hypertension
4. Patients with severe concurrent illness that would substantially limit life expectancy or require extensive systemic treatment
5. Patients with cognitive, language or hearing impairment severe enough to preclude participation
6. Additionally, patients were also excluded if his or her family member was a physician or nurse
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Changes in HbA1c level (target range <7.0%)<br>2. Changes in low density lipoprotein-cholesterol (LDL-C) concentration (target range <2.6mmol/L)<br>3. Changes in systolic and diastolic pressure (target range <130/80mmHg) <br>4. Change in urinary albumin excretion rate (UAER) (target range <30mg/d)<br>5. The HbA1c level was measured by a high-performance liquid chromatographic assay(Primus), with a normal reference range of 4.0% to 6.0%<br>6. Blood pressure was measured twice with a mercury sphygmomanometer in the right arm with the patient in a sitting position after a rest of 5 minutes <br>7. Serum LDL-C and urinary albumin concetration were determined by standard biochemical methods using a chemistry analyzer (Beckman Coulter Synchron clinical system DXC-800)
- Secondary Outcome Measures
Name Time Method 1. Measurement of: <br>1.1. Fasting plasma glucose (FPG)<br>1.2. Total cholesterol (TC)<br>1.3. Triglyceride (TG)<br>1.4. High density lipoprotein-cholesterol (HDL-C)<br>1.5. Depression screening by the Center for Epidemiologic Studies Depression Scale (CES-D)<br>2. Plasma glucose, TC, TG and HDL-C were determined by standard biochemical methods using a chemistry analyzer(Beckman Coulter Synchron clinical system DXC-800). <br>3. Depressive symptoms were evaluated by the CES-D scale which contains 20 items (range 0-60) where a score >16 is considered depressed