The variability of urinary albumin excretion and prevalence of microalbuminuria in young childre

Completed

• Conditions: microalbuminuria; proteins in the urine; 10057166; 10038430

• Registration Number: NL-OMON41927
• Lead Sponsor: niversitair Medisch Centrum Groningen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 110

Inclusion Criteria

- age 12-48 months
The inclusion of participants will be devided in two phases. In the first phase, 110 participants will be included, in which the variability of albuminuria will be studied. In the second phase an additional number of toddlers in the same age range will be included to determine the prevalence of microalbuminuria over the total study population. Once we know the day-to-day variability in albuminuria in this population we will be able to perform a powercalculation to determine the sample size for phase 2 of the study.

Exclusion Criteria

- Known renal disease of the child
- Current infection of the urinary tract

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Phase 1: The coefficient of variation (CV) of UAC calculated over 8 weeks time.<br /><br>Phase 2: The percentage babies and todders with a geometric mean of UAC><br /><br>20mg/L.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Phase 1: The CV of UAC calculated over 3 days<br /><br>Phase 2: The correlation of log transformed UAC with several parameters<br /><br>obtained from a questionnaire. </p><br>