Comparison of two complementary prebiotics in the treatment of Non-Alcoholic Fatty Liver
Phase 2
- Conditions
- on-Alcoholic Fatty Liver.Non-Alcoholic Fatty Liver (Non-Alcoholic Steato Hepatitis)
- Registration Number
- IRCT2014121620345N1
- Lead Sponsor
- Vice Chancellor for Research Yazd Shahid Sadoughi University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 72
Inclusion Criteria
age range 20-50 years with NAFLD(Non-Alcoholic Fatty Liver) confirmed by ultrasound; have not participated in other research projects. Exclusion criteria: history of alcohol consumption; dyslipidemia who are taking medications; pregnancy and lactation; history of high blood pressure; lung disease; kidney disease; liver transplantation; complications of diabetes and chronic disorders that cause aggregation of fat in the liver such as diabetes; hepatitis use of some drugs: such as Tamoxifen; blood pressure control; statins; insulin sensitivity enhancers; hepatotoxic drugs; birth control pills and estrogen.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Alanine Amino Transferase(ALT). Timepoint: Before and after 8 weeks. Method of measurement: Method :IFCC ( International Federation Clinical Chemistry) ? IU/L.;Aspartate Amin Transferase (AST). Timepoint: Before and after 8 weeks. Method of measurement: Method :IFCC ( International Federation Clinical Chemistry) ? IU/L.;Alkaline phosphatase (ALP). Timepoint: Before and after 8 weeks. Method of measurement: Method :IFCC ( International Federation Clinical Chemistry) ? IU/L.;TG (Triglyceride). Timepoint: Before and after 8 weeks. Method of measurement: Enzymatic (mg/dl).;TC (Total Cholesterol). Timepoint: Before and after 8 weeks. Method of measurement: Enzymatic (mg/dl).;LDL-C. Timepoint: Before and after 8 weeks. Method of measurement: Friedewald formula(mg/dl).;HDL-C. Timepoint: Before and after 8 weeks. Method of measurement: Deposit method(mg/dl).
- Secondary Outcome Measures
Name Time Method Serum Total Antioxidant Capacity (TAC). Timepoint: Before and after 8 weeks. Method of measurement: the DPPH (Diphenyl-2-Picrylhydrazyl) percentage reduction.;Serum Malon Di Aldehyde (MDA). Timepoint: Before and after 8 weeks. Method of measurement: based on Calorimetry.