Synovial Involvement in Development of Posttraumatic Osteoarthritis in Patients with Recurring Patellar Dislocations
Recruiting
- Conditions
- arthrosisosteoarthritis10023213
- Registration Number
- NL-OMON56210
- Lead Sponsor
- Radboud Universitair Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 25
Inclusion Criteria
16 years or older
Patients with a history of recurrent patellar dislocations of the index knee.
Exclusion Criteria
Patients with an active inflammatory or infectious co-morbid disease (including
rheumatic diseases).
Patients who had previous surgery on the index knee
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Marker expressions in the blood and mucosal tissue of patients with recurrent<br /><br>patellar (sub)luxation, indicating the inflammatory status of the patient.<br /><br>This will be linked to clinical data on pain and function at baseline.</p><br>
- Secondary Outcome Measures
Name Time Method <p>Correlation between RNA sequencing data on processes in the synovium and<br /><br>progression data on pain and function.</p><br>