Neuromuscular Responses to Acute Beetroot Ingestion in Women Older Adults
- Conditions
- Dietary SupplementPlacebo
- Interventions
- Dietary Supplement: beetroot juice
- Registration Number
- NCT05337527
- Lead Sponsor
- Universidad Francisco de Vitoria
- Brief Summary
Beetroot juice supplementation has shown the capacity for provoking different physiological effects (e.g. vasodilation and muscle contraction increments). However, the effects of beetroot juice ingestion on neuromuscular performance in women older adults are barely studied. In this randomized placebo-controlled study, we investigated the effects of beetroot acute supplementation in improving neuromuscular performance in women older adults
- Detailed Description
Beetroot juice supplementation has shown the capacity for provoking different physiological effects that could affect human performance (e.g. vasodilation and muscle contraction increments). Although this dietary supplement has been commonly used for improving sports performance in recreational or professional athletes, the scientific literature in older adults is scarce. Thus, in our knowledge, no previous studies have analyzed the side effects associated to ingestion in this population group. In this randomized placebo-controlled study, we investigated the effects of beetroot acute supplementation in improving neuromuscular performance and side effects associated with ingestion in women older adults.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 9
- Women >65 or <85 years of age.
- In good health, as determined by the investigator's review of history.
(based in previous studies on this topic (doi: 10.1093/gerona/glaa311).
Men and women <65 or >85 years of age Unable to provide informed consent Current smokers Significant orthopedic limitations or other contraindications to strenuous exercise Those taking proton pump inhibitors, antacids, xanthine oxidase inhibitors, or on hormone replacement therapy Those taking anti-coagulants or on anti-platelet therapy History of neuromuscular disease (e.g., cervical spondylotic radiculomyelpathy, lumbar spondylosis, amyotrophic lateral sclerosis, Guillain-Barré syndrome, and acquired demyelinating polyneuropathies) Cardiovascular disease (e.g., > stage I hypertension, heart failure, myocardial infarction/ischemia significant myocardial or pericardial diseases (e.g. amyloidosis, constriction), Moderate or severe valvular disease, renal disease, liver disease, or anemia
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Arm && Interventions
Group Intervention Description Beetroot supplementation beetroot juice One serving 70 mL of beetroot juice (6.4 mmol of NO3-; Beet-It-Pro Elite Shot, James White Drinks Ltd., Ipswich, UK) 3 h before initiating the testing session. Placebo supplementation beetroot juice One serving 70 mL of beetroot juice placebo (0.04 mmol of NO3-; Beet-It-Pro Elite Shot, James White Drinks Ltd., Ipswich, UK) 3 h before initiating the testing session.
- Primary Outcome Measures
Name Time Method Changes in maximal isometric handgrip strength (N) 1-week Using a dynamometer and measuring dominant/ non-dominant side
Changes in Sit and Stand Test 1-week Using Power Frail APP
Changes in Time Up and Go test 1-week Using a photocell timing gates (seconds)
Changes in 6-m gait speed test 1-week Using a photocell timing gates (seconds)
6-Minute Walk Test 1-week
- Secondary Outcome Measures
Name Time Method Side effects questionnarie 1-week Using a side-effects questionnarie (YES/NO scale)
Rate of perception effort (RPE) 1-week Using a validated scale (1-10 points)
Trial Locations
- Locations (1)
Universidad Francisco de Vitoria
🇪🇸Pozuelo de Alarcón, Madrid, Spain