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The effects of yohimbine on episodic memory retrieval and reconsolidation during EMDR

Conditions
Yohimbine, Emotional memory, EMDR, Eye movements, Noradrenalin, &#946
-adrenergic stress hormones
Registration Number
NL-OMON26672
Lead Sponsor
trecht University
Brief Summary

/A

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
Not specified
Target Recruitment
60
Inclusion Criteria

1. Passing the medical screening (blood pressure and heart rate examination and interview);

2. Age 18-50.

Exclusion Criteria

1. Systolic blood pressure over 140 mmHg, diastolic over 90 mmHg, and heart rate >100 beats per minute (bpm)

2. Familiarity with mechanisms behind EMDR

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The emotionality and vividness of recollected memories at pretest (baseline), posttest (after medication intake and each experimental manipulation) and after 24 hour follow-up measured with HR, SC, a 4-minute memory recall task, a VAS for emotionality, and a VAS for vividness.
Secondary Outcome Measures
NameTimeMethod
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