MORE DATa study
- Conditions
- total hip arthroplasty, knee arthroscopy, immune response, monocyte populations
- Registration Number
- NL-OMON24413
- Lead Sponsor
- Martini Hospital Groningen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 12
Inclusion Criteria
elective knee arthroscopy or an elective total hip arthroplasty (posterolateral approach) for primary osteoarthritis
-between 18 and 70 years of age
Exclusion Criteria
-pre-existing immune deficiency
-use of immunosuppressant drugs
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Expression of early and late markers that identify the maturation stage of monocyte subpopulations.
- Secondary Outcome Measures
Name Time Method -Absolute numbers of monocyte subpopulations and lymphocyte populations.<br /><br>-Serum interleukines and classical tissue damage marker (CRP and CK) levels.<br>