Clinical outcomes of locally advanced oral cavity cancers treated with definitive radiotherapy by VMAT technique
Not Applicable
- Conditions
- Health Condition 1: C00-C14- Malignant neoplasms of lip, oral cavity and pharynx
- Registration Number
- CTRI/2024/02/062620
- Lead Sponsor
- Sri venkateswara institute of medical science
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Histo-pathologically proven squamous cell carcinoma [SCC] of lips, buccal mucosa, tongue, gingiva, hard palate, retro molar trigone, floor of mouth.
2.Age : 18 -70 years .
3.Patients with eastern cooperative oncology group [ECOG] performance status of 0-2 .
4.Stage III to IVb SCC of oral cavity [american joint committee on cancer : 8th edition].
5.Patients with stage III to IVb SCC of oral cavity, not willing for surgery.
Exclusion Criteria
1. Cancer with distant metastasis.
2. Patient with ECOG performance status of 3-4.
3. Patients who have undergone surgery.
4. Patients previously treated with radiotherapy to head & neck region.
5. Pregnant and lactating mothers.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To estimate TUMOR RESPONSE in locally advanced oral cavity cancers treated by volumetric modulated arc radiotherapy with curative intentTimepoint: 3 months post radiotherapy
- Secondary Outcome Measures
Name Time Method •ACUTE TOXICITIES- <br/ ><br> <br/ ><br>•Mucositis <br/ ><br>•Dermatitis <br/ ><br>•Dysphagia <br/ ><br>•Xerostomia <br/ ><br>Timepoint: Weekly during radiotherapy and monthly up to 3 months post radiotherapy;•LATE TOXICITIES- <br/ ><br> <br/ ><br>•Dysphagia <br/ ><br>•Xerostomia <br/ ><br>•Dermatitis <br/ ><br>•Mucositis <br/ ><br>Timepoint: Every 3 monthly up to 1 year post radiotherapy