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Comparison of the number of oocytes obtained by performing ovarian stimulation at the time of the menstrual cycle that is usually done with performing it at a later stage of the cycle in patients who have previously had a poor response

Phase 1
Conditions
Suboptimal response of ovarian stimulation
Therapeutic area: Body processes [G] - Reproductive physiologi cal processes [G08]
Registration Number
EUCTR2019-001342-18-ES
Lead Sponsor
Instituto Bernabeu
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Recruiting
Sex
Female
Target Recruitment
41
Inclusion Criteria

338/5000
1. Less than 10 oocytes in a conventional pre-controlled ovarian stimulation protocol
2. Age <41 years
3. BMI between 18 and 32 kg / m2
4. Regular menstrual cycles between 21 and 35 days.
5. Indication of in vitro fertilization
6. Indication to start the stimulation with 150mcg of corifolitropin alfa
7. Presence of both ovaries
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 41
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

1. Presence of follicles larger than 10 mm in the randomization visit
2. Endometriosis III / IV
3. Bologna criteria: patients with less than 4 oocytes in a previous ovarian stimulation and poor ovarian reserve parameters
4. Concurrent participation in another study

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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