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Dynamics of Stroke Volume and Cardiac Output During Parabolic Flight, and Its Relationship to Intravascular Volume

Not Applicable
Completed
Conditions
Healthy Volunteers
Registration Number
NCT02518880
Lead Sponsor
University Hospital, Caen
Brief Summary

To understand the cardiovascular reactions of the human body to changing conditions of gravity is an important aim of space science. In this context, cardiac output (CO) is a key value to estimate the human cardiovascular system.

The main objective of this experiment is to determine the effects of parabolic flight on intravascular volume, and how these changes modulate the complex haemodynamics induced by the parabolas.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
18
Inclusion Criteria
  • healthy volunteers (men or women),
  • aged from 18 to 55,
  • affiliated to a Social Security system,
  • who accept to take part in the study,
  • who have given their written stated consent,
  • who already participated in parabolic flights (even in the same campaign)
  • All subjects will pass a medical examination similar to a standard aviation medical examination for private pilot aptitude. There will be no additional test performed for subject selection
Exclusion Criteria
  • person who took part in a previous biomedical research protocol, of which exclusion period is not terminated,
  • pregnant women

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Primary Outcome Measures
NameTimeMethod
haemoglobin concentrationbaseline
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Umr Ucbn/Inserm U1075 Comete

🇫🇷

Caen CEDEX, Basse-Normandie, France

Umr Ucbn/Inserm U1075 Comete
🇫🇷Caen CEDEX, Basse-Normandie, France

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