NCT02518880CompletedNot Applicable
Dynamics of Stroke Volume and Cardiac Output During Parabolic Flight, and Its Relationship to Intravascular Volume
Conditions
Interventions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- University Hospital, Caen
- Enrollment
- 18
- Locations
- 1
- Primary Endpoint
- haemoglobin concentration
Study Overview
Brief Summary
To understand the cardiovascular reactions of the human body to changing conditions of gravity is an important aim of space science. In this context, cardiac output (CO) is a key value to estimate the human cardiovascular system.
The main objective of this experiment is to determine the effects of parabolic flight on intravascular volume, and how these changes modulate the complex haemodynamics induced by the parabolas.
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Intervention Model
- Single Group
- Primary Purpose
- Basic Science
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to 55 Years (Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •healthy volunteers (men or women),
- •aged from 18 to 55,
- •affiliated to a Social Security system,
- •who accept to take part in the study,
- •who have given their written stated consent,
- •who already participated in parabolic flights (even in the same campaign)
- •All subjects will pass a medical examination similar to a standard aviation medical examination for private pilot aptitude. There will be no additional test performed for subject selection
Exclusion Criteria
- •person who took part in a previous biomedical research protocol, of which exclusion period is not terminated,
- •pregnant women
Arms & Interventions
Plasma volume measurements
Other
Intervention: Parabolic flight (Other)
Plasma volume measurements
Other
Intervention: plasma volume measurements (Other)
Outcomes
Primary Outcomes
haemoglobin concentration
Time Frame: baseline
Secondary Outcomes
No secondary outcomes reported
Investigators
Study Sites (1)
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