A study on the association between mast cell number in skin, itch and quality of life in patients with Psoriasis
Not Applicable
- Conditions
- Health Condition 1: L400- Psoriasis vulgaris
- Registration Number
- CTRI/2023/10/058689
- Lead Sponsor
- Regina Jacob Brahmakulam
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients consenting for the study who have been diagnosed with Psoriasis Vulgaris either based on typical clinical features and/or histopathological criteria. Patients should be off topical and oral treatment for psoriasis for the past 2 months either due to drug default, new flare in previously controlled disease, or in a treatment-naive patient.Patients will not be asked to withhold the treatment for study purposes.
Exclusion Criteria
Patients who have a history of atopy, bronchial asthma, allergic rhinitis, chronic sponatneous urticaria, angioedema, monoclonal mast cell activation syndrome and mastocytosis.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method mast cell number (density) between lesional and peri-lesional skin of the same patientsTimepoint: at baseline
- Secondary Outcome Measures
Name Time Method 5-D itch score, PASI and DQLITimepoint: at the same time of sample taking