Density and function of mast cells in breast cancer: influence on recurrence-free and disease-specific survival

• Conditions: C50; Malignant neoplasm of breast

• Registration Number: DRKS00033276
• Lead Sponsor: Helios Klinikum Krefeld - Institut für Pathologie

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-12-28
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 96

Inclusion Criteria

Malignant tumor of the mammary gland

Exclusion Criteria

No follow-up data

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary project goal is the functional in situ characterization of mast cells and the mast cell-specific enzymes.

Secondary Outcome Measures

Name	Time	Method
The secondary project goal discusses whether there is any evidence to block the interaction of vasoactive substances in the tumor area with mast cell stabilizers. Furthermore, a secondary project goal would be to determine whether effects could be achieved with increased levels of histamine decarboxylase with histamine blockers.