Effect of Lighting Supplementation on Daytime Cognition

Not Applicable

• Conditions: Non-visual Effects of Light
• Interventions: Device: Visible light

• Registration Number: NCT04745312
• Lead Sponsor: Brigham and Women's Hospital

Brief Summary

The aim of the study is to examine the efficacy of supplementing sub-optimal ambient room lighting with a task lamp on working memory and procedural learning.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2021-02-04
• Study First Submitted QC: 2021-02-04
• Study First Posted: 2021-02-09
• Study Start: 2021-03-01
• Status Verified: 2022-02
• Last Update Submitted: 2022-02-16
• Last Update Posted: 2022-02-18
• Primary Completion: 2022-03-01
• Study Completion: 2022-03-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 16

Inclusion Criteria

• Aged between 18-30 years;
• Healthy (no medical, psychiatric or sleep disorders;
• Non-smoking for at least 6 months;
• Body Mass Index of >18 or <30 kg/m2;
• Able to maintain 7-hour consistent sleep schedule during the study
• Able to refrain from caffeine, alcohol, medication and supplements during the study

Exclusion Criteria

• History of alcohol or substance abuse;
• positive result on drugs of abuse urine toxicology;
• Current or past history of sleep disorders, including but not limited to obstructive sleep apnea, narcolepsy, insomnia, or any significant sleep complaint
• Psychiatric disorder, or first degree relative with a psychiatric disorder
• Recent acute or chronic medical disorder
• Use of drugs or medication (birth control OK) likely to affect sleep, alertness or light sensitivity, as determined by the investigators
• Visual disorder, including but not limited to color blindness, or family history of glaucoma
• Pregnancy or lactation
• Shift work (> 2 nights / week in the last 3 months and not during the study)
• Transmeridian travel (2 or more time zones) in the past 3 months
• Any other reason as determine by the Principal Investigator

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Ambient light	Visible light	Fluorescent ambient lighting
Ambient light plus task lamp	Visible light	Fluorescent ambient lighting plus task lamp

Primary Outcome Measures

Name	Time	Method
Working memory	8 hour light exposure	Percent correct responses on a 2-minute mental arithmetic task

Secondary Outcome Measures

Name	Time	Method
Procedural learning	8 hour light exposure	Percent change in the number of correct sequences on the Motor Sequence Task

Trial Locations

Locations (1)

Brigham and Women's Hospital; 🇺🇸 Boston, Massachusetts, United States