NCT02407574Unknown不适用
Assessment of the Force Frequency Relationship of the Myocardium After On-pump CABG Surgery
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 20
- 主要终点
- End-systolic elastane of the left ventricle.
研究概览
简要总结
The aim of the study is to determine whether increasing the heart rate by epicardial atrial pacing after surgery improves the contractile force of the myocardium. After complete weaning from CPB, several pressure-loops of the LV will be recorded at different levels of preload using transoesophageal echo, invasive blood pressure monitoring. The preload will be manipulated by adding fluid from the CPB reservoir or draining fluid into the CPB reservoir.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •CABG only surgery
- •Preopeartive LVEF ≥ 53 %
- •Use of epicardial pacing wires to assist CPB weaning
排除标准
- •Contra-indication to TEE
- •AV block at the time of CPB weaning
- •Sinus rhythm less than 50 or more than 90 BPM after CPB weaning.
结局指标
主要结局
End-systolic elastane of the left ventricle.
时间窗: 30 minutes after CPB weaning
次要结局
未报告次要终点
研究者
Jean François Brichant
Professor, Head of Department
University of Liege
相似试验
已完成
不适用
Atrial Electromechanical Interval and Pulse Wave Velocity in the Prediction of Recurrence of Atrial FibrillationAtrial FibrillationNCT00818012Creighton University129
已完成
不适用
Effects of Heart Rates and Variability of Heart Rates on Image Quality of Dual-Source CT Coronary AngiographyCTCoronary AngiographyNCT00632918Far Eastern Memorial Hospital149
已完成
1 期
A Study of LY2484595 on the Electrical Activity of the HeartHealthy VolunteersNCT01537887Eli Lilly and Company72
已完成
4 期
VERRARI - "Are Ventricular Arrhythmic Episodes Reduced by Rate Response in ICDs?"Ventricular FibrillationNCT00180427Guidant Corporation75
已完成
不适用
Acoustic Cardiographic Assessment of Heart Function and the Role of Phrenic Nerve StimulationCardiac Pacing, ArtificialTranscutaneous Electric Nerve StimulationHeart Failure, CongestiveNCT00541541Luzerner Kantonsspital