NCT02407574
Unknown
N/A
Assessment of the Force Frequency Relationship of the Myocardium After On-pump CABG Surgery
ConditionsAdult Cardiac Surgery
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Adult Cardiac Surgery
- Sponsor
- University of Liege
- Enrollment
- 20
- Primary Endpoint
- End-systolic elastane of the left ventricle.
- Last Updated
- 11 years ago
Overview
Brief Summary
The aim of the study is to determine whether increasing the heart rate by epicardial atrial pacing after surgery improves the contractile force of the myocardium. After complete weaning from CPB, several pressure-loops of the LV will be recorded at different levels of preload using transoesophageal echo, invasive blood pressure monitoring. The preload will be manipulated by adding fluid from the CPB reservoir or draining fluid into the CPB reservoir.
Investigators
Jean François Brichant
Professor, Head of Department
University of Liege
Eligibility Criteria
Inclusion Criteria
- •CABG only surgery
- •Preopeartive LVEF ≥ 53 %
- •Use of epicardial pacing wires to assist CPB weaning
Exclusion Criteria
- •Contra-indication to TEE
- •AV block at the time of CPB weaning
- •Sinus rhythm less than 50 or more than 90 BPM after CPB weaning.
Outcomes
Primary Outcomes
End-systolic elastane of the left ventricle.
Time Frame: 30 minutes after CPB weaning
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