The Correlation Between Sevoflurane and qNOX

Completed

• Conditions: Analgesic Adverse Reaction; Nociceptive Pain; Inhalation; Vapor

• Registration Number: NCT03665792
• Lead Sponsor: China International Neuroscience Institution

Brief Summary

This study purpose to observation the sevoflurane analgesia effect, and using nociception real-time monitoring NOX to test the correlation between the sevoflurane and NOX index.

Detailed Description

This study purpose to observation the sevoflurane analgesia effect, and using nociception real-time monitoring NOX to test the analgesia effect of the sevoflurane.

And test the correlation between the sevoflurane and NOX index.

Study Timeline

• Study First Submitted: 2018-08-04
• Study First Submitted QC: 2018-09-08
• Study First Posted: 2018-09-11
• Study Start: 2019-02-11
• Primary Completion: 2019-09-01
• Study Completion: 2019-09-01
• Status Verified: 2020-01
• Last Update Submitted: 2020-01-20
• Last Update Posted: 2020-01-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 58

Inclusion Criteria

1. Elective thoracoscope surgery patients
2. Age ranging from 25 to 85 years
3. American Society of Anesthesiologists (ASA) Physical Status score of 2 to 4
4. a body mass index (BMI) ranging from 18.5 to 40 kg/m2.

Exclusion Criteria

1. Clinical diagnosis of Alzheimer's Disease
2. implanted pacemaker
3. Clinical diagnosis of psychiatric diseases
4. Clinical diagnosis of epilepsy
5. Clinical diagnosis of autonomic nervous system disorders which might affect the EEG

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The sevoflurane application correlated with the qNOX index	through study completion, an average of 1 year	The sevoflurane application correlated with the qNOX index, meanwhile reflect the analgesia effect of sevoflurane application

Trial Locations

Locations (1)

Bei Liu; 🇨🇳 Beijing, Beijing, China