Multimodal characterization of inflammatory processes in myocarditis by combined [18F]FDG-PET/MRT
Not Applicable
Recruiting
- Conditions
- I40I41Acute myocarditisMyocarditis in diseases classified elsewhere
- Registration Number
- DRKS00014634
- Lead Sponsor
- niversitätsklinikum Tübingen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 150
Inclusion Criteria
Patients with clinical proved or suspected inflammation of the myocardium,
warrant clinical indication for a [18F]FDG-PET examination,
age: =18 years,
written informed consent.
Exclusion Criteria
Pregnant and/or breast feeding women,
contra-indication for a MR-examination,
contra-indication for gadolinium-based contrast agend,
adiposities with >150 kg body weight
limited capacity to consent.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Correlation of functional MR-parameters (particularly T1/T2-mapping) and [18F]FDG-PET with spatial separated tissue characterizations of the myocarditis during PET/MRT.
- Secondary Outcome Measures
Name Time Method Application of a MR-based PET-motion correction to improve the spatial accuracy and image quality of the PET acquisition.<br>establishment of a workflow for heart PET/MRT,<br>improvement of patient’s comfort.<br>Differentiation of inflammation into active vs. healed.<br>