Comparing the effect of electroconvulsive therapy (ECT) with or without sodium valproate on cognitive impairments and treatment response in patients with bipolar disorder with manic episode
Phase 2
- Conditions
- Bipolar disorder.Bipolar affective disorder
- Registration Number
- IRCT201608049014N108
- Lead Sponsor
- Vice-chancellor for Research the Technology, Zahedan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
bipolar disorder with manic episode; Indication of electroconvulsive therapy.
Exclusion criteria: having other psychiatric disorders; contraindication for ECT; drug abuse; using anti-convulsion medications beside sodium valproate.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Cognitive impairment. Timepoint: before and one month after treatment. Method of measurement: using Minimal Mental State Exam (MMSE).;Severity of mania. Timepoint: before and one month after treatment. Method of measurement: using Young Mania Rating Scale (YMRS).
- Secondary Outcome Measures
Name Time Method