ketamine role in depression treatment
Not Applicable
- Conditions
- Major Depression.
- Registration Number
- IRCT201104092266N2
- Lead Sponsor
- Isfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
IInclusion Criteria:
Known case of major depressive disorder without psychotic feature based on DSM IV-TR who Referred to ECT by a psychiatrist; age between 20-50 years; signing the consent form.
Exclusion Criteria
History of psychosis or being psychotic; substance abuse during recent 3 months; breast feeding mothers; having medical incapacitating disease such as: renal, hepatic, gastro intestinal, cardiovascular, endocrine, neurologic and hematologic disease based on history and clinical and Para clinical evaluations; history of seizure with unknown origin; uncontrolled hypo or hyper thyroidism ; simultaneous another psychiatric interventions
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Severity of major depressive symptoms. Timepoint: prior to each intervention session, one week, 1,2 and 3 month afer intervention. Method of measurement: structured interviewe based on Hamilton Depressive Rating Scale.
- Secondary Outcome Measures
Name Time Method Cognitive Side effects. Timepoint: Prior to intervention, one week and one month after intervention. Method of measurement: Adult Wechsler Memory Scal.