Fomentation therapy in management of multiple joint pain

Phase 2/3

Not yet recruiting

• Conditions: Rheumatoid arthritis, unspecified. Ayurveda Condition: AMAVATAH,

• Registration Number: CTRI/2025/05/087424
• Lead Sponsor: Dr Aishwarya P

Brief Summary

Amavata(1) is one of the commonest disorder which is caused due to agni dushti, along with the formation of ama and vitiation of vatadosha which occupies specific Shleshma stanas i.e. multiple Sandhies which results in severe Shoola(pain), Shotha(swelling), Stabdatha (stiffness) along with Sarvadaihika lakshanas of ama. The clinical presentation of Amavata may be closely correlated with that of Rheumatoid arthritis irrespective of etiological factors.Rheumatoid Arthritis(2) is a chronic inflammatory disorder of autoimmune origin that may effect many tissues and organs but principally attacks the joints producing non suppurative proliferative and inflammatory synovitis. The prevalence of RA is approximately 0.24% to 1% of population. In India, the prevalence of RA is 0.5% to 0.75%.Peak incidence in third-fourth decades with 3-5 times higher in females.The management in Modern science includes the use of NSAID’s (Nonsteroidal anti-inflammatory Drugs), Glucocorticoids, DMARD’s (Disease Modifying Anti rheumatic Drugs), immunosuppressive therapies.In spite of advancement in management of Rheumatologic Disorders, the patients with Rheumatoid Arthritis are treated with drugs which on prolong usage causes hepatotoxicity. Panchakarma therapy is such a unique module of management which gives beneficial effect. Ayurveda classics has given a detailed description regarding the management(3) of Amavata which includes Langhana, Swedana, Deepana with Katu and Tikta Rasa Dravyas, Virechana, Basti, ruksha sweda and ruksha upanaha.Lavana(4) is having laghu, Deepana, Kaphavatahara and Shulaghna properties. Hence in the present study Samudra lavana (Crystal salt) is taken as Swedana material for Sarvanga lavana pottali sweda.Aavi Kizhi is a combination of Bashpa and Pottali sweda by using Dashamoola and Amrutha choorna.Dashamoola and Amrutha(5) are having Shothahara, Deepana, Pachana, Vatakaphahara, and Jwarahara properties. Hence in the present study Dashamoola and Amrutha choorna are used as Swedana material for Sarvanga Aavi Kizhi.Eranda taila(6) is considered as best for Amavata. It has properties like Snigdha, Tikshna, Sukshma guna, Madhura vipaka and Ushna virya. It does both Vatakaphahara, Deepana, and Sroto shodhana karma that helps to tackle Amavata.As the disease has mainly predominance of Ama and Vata dosha, the present study is planned to achieve Vatahara and Ampachana through two different Sankara swedas i.e.,Sarvanga Lavana pottali sweda to one group and Sarvanga Aavi kizhi to other group, where both the group receive Nitya Virechana withGandharvahasta taila.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2025-05-22
• Study Start: 2025-06-16

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• 1.Subjects who fulfill diagnostic criteria of Rheumatoid arthritis/Amavata irrespective of gender, religion, occupation and age group between 18-60 years will be included.
• 2.Subjects with or without on DMARD medications will be included.
• 3.Subjects fit for Swedana.
• 4.Subjects fit for Nitya virechana.
• 5.Both sero positive and sero negative subjects of RA .

Exclusion Criteria

• 1.Subjects with other systemic diseases like uncontrolled Diabetes mellitus, uncontrolled hypertension, which would interfere the present study.
• 2.Subjects of other connective tissue disorders like SLE, polymyositis, scleroderma etc, other than RA.
• 3.Subjects who have developed extra-articular complications of RA like pleural effusions, myocarditis, vasculitis etc.
• 4.Pregnant and lactating women.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Reduction in pain, swelling, stiffness of the joints involved	0th day and 7th day

Secondary Outcome Measures

Name	Time	Method
Reduction in joint tenderness	8 days

Trial Locations

Locations (1)

JSS Ayurveda Medical college and Hospital, Mysuru; 🇮🇳 Mysore, KARNATAKA, India

JSS Ayurveda Medical college and Hospital, Mysuru

🇮🇳Mysore, KARNATAKA, India

Dr Aishwarya P

Principal investigator

8073050830

aishwaryaaishu70944@gmail.com