A study to compare the effectiveness of two different doses of oral Pregabalin,given before surgery,in reducing post operative pain after abdominal surgery under spinal anesthesia
Not Applicable
Completed
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2017/07/008978
- Lead Sponsor
- Azeezia Medical College
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients of either sex,between age 18 years-65years,ASA physical status 1-2,who are scheduled for infraumbilical laprotomy under Spinal Anesthesia and are willing and able to give informed consent will be recruited to the trial
Exclusion Criteria
Patients with
1.known drug allergy to pregabalin
2.uncontrolled hypertension
3.uncontrolled diabetes mellitus
4.ischemic heart disease
5.cerebrovascular disease
6.renal and hepatic disease
7.history of alcohol and drug abuse
8.any general contraindications for spinal anaesthesia
9.chronic pain and neurological disorders
10.on NSAIDâ??s and on other analgesics
11.Pregnancy and lactation
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 24 hour total rescue analgesic (diclofenac +/-pentazocine) consumptionTimepoint: At 24 hours post operatively.
- Secondary Outcome Measures
Name Time Method Reduction of postoperative pain scores,Time to first requirement of rescue analgesia, Recovery time from sensory block and Tolerability of the used doses represented by the side effects.Timepoint: at 4,8,12,16,20 and 24 hours post operatively.