Efficacy of high dose vitamin d on smear positive pulmonary tuberculosis treatment

Phase 2

• Conditions: Smnear positive pulmonary tuberculosis.; Tuberculosis of lung, confirmed by sputum microscopy with or without culture

• Registration Number: IRCT2013061610326N1
• Lead Sponsor: Hormozgan University of MedicalSciences, research and technology department

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

1- age of 18-65 years 2- inclined to participate in the study 3- smear positive pulmonary tb 4- has not started antituberculous treatment 5- does not use vitamin d supplement
Exclusion criteria: 1- use of antituberculous treatment regimen 2-extrapulmonary or smear negative tb 3-immunosuppresion, HIV/AIDS, renal insufficiency, hepatic failure, diabetes, organ transplant, sarcoidosis, hyperparathyroidism 5- treatment with corticosteroids, thiazides 6-symptomatic cardiac disease 7- allergy to antituberculous medications or intolerance to complete the treatment 8-concommitant consumption of drugs interacting with vitamin d levels (i.e phenytoin, phenobarbital, carbamazepin, theophylline) 9-unable to give consent to participate in the study or inability to complete the study 10-Death of the patient

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Sputum conversion. Timepoint: At the initiation of treatment and six months after. Method of measurement: Sputum smear.