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EFFICACY OF INTRA-ARTICULAR TRANEXAMIC ACID IN PRIMARY UNILATERAL TOTAL KNEE ARTHROPLASTY: A PRELIMINARY STUDY

Not Applicable
Registration Number
CTRI/2010/091/001260
Lead Sponsor
Dr. O. N. Nagi, Chairman, Joint Replacement and Reconstruction Unit, Sir Ganga Ram Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Open to Recruitment
Sex
Not specified
Target Recruitment
90
Inclusion Criteria

Patients diagnosed with osteoarthritis scheduled for unilateral cemented TKA, either sex, aged <80 years

Exclusion Criteria

Patients with known allergy to tranexamic acid, hepatic/cardio-respiratory/renal insufficiency, congenital or acquired coagulopathy, recent history of thrombo-embolic episode

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Blood Loss, measured by drain output drop in Hb and PCVTimepoint: up to 5th day after surgery
Secondary Outcome Measures
NameTimeMethod
Requirement of blood transfussionTimepoint: Course of inpatient stay after total knee arthroplasty
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