Is there a role for Helicobacter pylori eradication in the treatment of laryngopharyngeal reflux? : A double blinded randomised case controlled clinical trial - H.pylori erradication in laryngopharyngeal rteflux.
- Conditions
- ARYNGOPHARYNGEAL ACID REFLUX
- Registration Number
- EUCTR2004-001633-42-GB
- Lead Sponsor
- HS GRAMPIA
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
LARYNGOPHARYNGEAL REFLUX AS PROVEN ON HISTORY AND FULL EXAMINATION
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range
Exclusion Criteria
1- UPPER AERODIGESTIVE TRACT MALIGNANCY
2- OTHER LARYNGEAL PATHOLOGY
3- PATIENTS CURRENTLY ON PROTON PUMP INHIBITOR THERAPY
4 - PATIENTS INVOLVED IN ANY OTHER CLINICAL TRIAL
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Main Objective: TO ESTABLISH IF PATIENTS WITH LARYNGOPHARYNGEAL REFLUX HAVE HELICOBACTER PYLORI IN THERE DIGESTIVE TRACT;Secondary Objective: TO ESTABLISH IF ERADICATION OF HELICOBACTER PYLORI IMPROVES SUBJECTIVE SYMPTOMS AND OBJECTIVE SIGNS OF LARYNGOPHARYNGEAL REFLUX;Primary end point(s): 1- POSITIVE UREA BREATH TEST<br>2- REFLUX SYMPTOM INDEX SCORING SYSTEM PRE AND POST TREATMENT<br>3- REFLUX FINDINGS SCORING SYSTEM PRE AND POST TREATMENT<br>
- Secondary Outcome Measures
Name Time Method